Iodine and Thyroid Nutrients
116 associated posts. These are attributed summaries; original text remains at the linked X post and in the local archive.
- @lowmegatron · 2025-10-01 original
Author asserts that thyroid hormone regulates energy and that energy determines everything. The quoted post, from another account, is an anecdote that the user became less prone to sickness after starting thyroid supplementation.
Source summary and thread relationship - @lowmegatron · 2025-10-01 original
Author claims stearic acid limits the cancer-promoting effects of seed oils. Support cited is rat and mouse abstracts in which stearic acid reduced or delayed tumours and lowered linoleic acid in tissues. The author also notes centenarians' fondness for chocolate. The quoted post from another account claims polyunsaturated fats are required for skin cancer and saturated fat protected mice.
Source summary and thread relationship - @lowmegatron · 2025-10-02 original
The post quotes Ray Peat saying that in the 1930s thyroid removal raised blood cholesterol and thyroid supplementation lowered it. He says thyroid promotes conversion of cholesterol to pregnenolone and progesterone. The embedded metabolicwave post is a Ray Peat clip on the cholesterol-lowering effect of thyroid.
Source summary and thread relationship - @lowmegatron · 2025-10-04 original
Author says winter's lower light and cold-stress free fatty acids suppress thyroid activity. Quoted Ray Peat passages say thyroid supplement needs can be four times higher in December than July, and recommend bright incandescent or full-spectrum light and limiting unsaturated fats and tryptophan.
Source summary and thread relationship - @lowmegatron · 2025-10-06 original
Post shares a Ray Peat quote saying low thyroid is accompanied by extra antibody production, including antibodies to the thyroid itself, as part of a cleanup process. Per the quote, antibody production stops when inflammation stops, and circulating antibodies take several months to disappear. The embedded quoted post (lowmegatron) gives a longer Ray Peat excerpt on Hashimoto's, iodine, TSH and antibodies.
Source summary and thread relationship - @lowmegatron · 2025-10-08 original
Author says light therapy plus supplements beat supplements alone in a Turkish human study of Hashimoto's, with higher T3, higher T3/T4 ratio, lower TPOAb and lower L-thyroxin dose. The post gives the laser protocol and comments on the supplements used.
Source summary and thread relationship - @lowmegatron · 2025-10-08 original
Author reports a Kosovo study in which three weeks of near-infrared light therapy added to selenium/vitamin D was followed by improved thyroid labs and reduced weight and waist measures in Hashimoto's. The post gives the light parameters and says weight fell further at 6 months.
Source summary and thread relationship - @lowmegatron · 2025-10-08 original
Author reports a Kosovan study in which three weeks of near-infrared light therapy plus supplements was followed by lower thyroid volume and improved thyroid labs in Hashimoto's. The post says the share of patients with normal thyroid volume rose from 17% to 96% at 6 months.
Source summary and thread relationship - @lowmegatron · 2025-10-11 original
Author posts a checklist of factors for thyroid hormone T3: carbohydrates, calories, several vitamins and minerals, low stress, and moderate protein.
Source summary and thread relationship - @lowmegatron · 2025-10-13 original
The author promotes the Hypothyroid Masterclass, a video course with a support community, aimed at people whose thyroid labs are 'normal' but who feel hypothyroid. The post lists the course modules. The quoted post is only a link.
Source summary and thread relationship - @lowmegatron · 2025-10-14 original
The post quotes Ray Peat saying the skin test for iodine deficiency is unscientific because reductants convert iodine to colorless iodide. The embedded quoted post from lowmegatron quotes text linking excess iodide to autoimmune thyroiditis and adds a bracketed comment about selenium, vitamins C and E, and polyunsaturated fats.
Source summary and thread relationship - @lowmegatron · 2025-10-21 original
The post advertises the Hypothyroid Masterclass, described as teaching practical testing, nutrition and dosing concepts with a support community, and lists its video modules. The embedded quoted post from lowmegatron contains only an emoji and a t.co link.
Source summary and thread relationship - @lowmegatron · 2025-10-26 original
The post is only a thread title and link on selenium, thyroid hormones, autoimmunity and Hashimoto's. No substantive health claims are in the retrieved text.
Source summary and thread relationship - @lowmegatron · 2025-10-29 own thread
lowmegatron says iodine is essential for thyroid hormone synthesis but that deficiency and high doses can both cause thyroid problems, including hypothyroidism, hyperthyroidism or autoimmunity in susceptible people. He cites the RDA of 150 mcg, says intakes above 300 mcg daily may pose risks, and names seafood and dairy as good sources. The quoted parent context (a Ray Peat quote and PMID 25050783 on excess iodine and thyroiditis) is context, not part of this post's own text.
Source summary and thread relationship - @lowmegatron · 2025-10-29 own thread
lowmegatron claims goitrogens, mainly cruciferous vegetables and soy products, can interfere with thyroid hormone levels even before a goiter appears. He says cooking reduces them, so raw or lightly cooked foods are riskier, and that iodine insufficiency increases their effect.
Source summary and thread relationship - @lowmegatron · 2025-11-07 original
The author defines goiter and quotes a passage, with no source named in the post, about soybean-diet goitrogenic effects in animals and case reports of goiter in infants on soy products, including regression after switching to goat's milk. The author adds that extra iodine is sometimes proposed as a solution but excess iodine can cause thyroid problems. The embedded lowmegatron post quotes Ray Peat on beans and hypothyroidism.
Source summary and thread relationship - @lowmegatron · 2025-11-11 original
The post shares a Ray Peat quotation: avoid fluoridated water where possible. It says bromate and polybrominated biphenyls are definitely toxic but simple bromide is not very toxic, and that iodine-supplement promoters give a wrong impression of bromine. The embedded quoted post by lowmegatron claims prenatal fluoride exposure is associated with lower child cognitive scores.
Source summary and thread relationship - @lowmegatron · 2025-11-11 original
The post claims fluoridated water doubles hypothyroidism rates. It notes fluoride was used in the 1950s to suppress thyroid activity in hyperthyroidism and quotes a study comparing practices in the West Midlands (fluoridated) and Greater Manchester (non-fluoridated). It also quotes statements that fluoride is an endocrine disruptor, especially where iodine intake is inadequate. The embedded quote is a Ray Peat statement about avoiding fluoridated water and about bromide.
Source summary and thread relationship - @lowmegatron · 2025-11-12 original
Author shares a Ray Peat quote saying inositol seems safe at a few grams/day and may protect against cataracts, and adds that inositol can help lower thyroid autoimmunity. The quoted lowmegatron post claims selenium plus myo-inositol lowers thyroid antibodies and TSH in hypothyroidism, and gives dietary sources.
Source summary and thread relationship - @lowmegatron · 2025-11-14 original
Author reminds readers that excess iodine causes autoimmune thyroid problems, with greater risk in people with prior iodine deficiency or thyroid issues. A quoted abstract (PMID 25050783) links excess iodide to autoimmune thyroiditis and proposes mechanisms.
Source summary and thread relationship - @lowmegatron · 2025-11-15 original
The author shares a Ray Peat quote suggesting alcohol cravings may relate to hypothyroidism, because high serotonin activity is often present and alcohol may temporarily compensate. The embedded post from lowmegatron claims low-dose alcohol improves glymphatic drainage in mice, while higher doses impair it.
Source summary and thread relationship - @lowmegatron · 2025-11-16 original
Post shares a Ray Peat quote on improving thyroid hormone conversion: selenium deficiency correction works quickly, intestinal flora problems must be addressed, and other nutritional factors such as daily raw carrot, weekly seafood and liver, sunlight, vitamin D and calcium-to-phosphate balance are often helpful. The embedded post is a lowmegatron thread on selenium and thyroid, whose content is not included.
Source summary and thread relationship - @lowmegatron · 2025-11-17 original
Author states that pregnenolone lowers stress and reduces alcohol cravings at 300-500 mg/day and quotes a trial abstract (PMID 36445398) reporting reduced stress- and cue-induced craving in individuals with alcohol use disorder. The quoted post shares a Ray Peat quote linking alcohol cravings to hypothyroidism and high serotonin.
Source summary and thread relationship - @lowmegatron · 2025-11-24 original
The author comments that a person was 'one-shotted by excessive iodine'. The quoted account (RealitysaGame) says they went overboard with an unnamed item ('this'), ended up in thyroid crisis, and needed a couple of months to get it under control. The quoted account advises not to overdo it, without saying not to try it.
Source summary and thread relationship - @lowmegatron · 2025-11-24 original
The author advertises the Hypothyroid Masterclass, a video course with a support community, aimed at people with normal thyroid labs who still feel hypothyroid. Most of the post is a list of module topics.
Source summary and thread relationship - @lowmegatron · 2025-11-26 original
The posting author argues that seed oil (linoleic acid) intake probably plays a large role in Hashimoto's susceptibility, citing a rodent study where a high-linoleic-acid diet was followed by thyroid autoimmunity and hypothyroidism. The author links this to lipid peroxidation and says seed oils are tied to other autoimmune diseases partly via pro-estrogenic properties. The embedded quoted post (lowmegatron) cites register data on suicide and unknown-cause death in Hashimoto's and gives that account's opinion that inadequate treatment, T3 and temperature are involved.
Source summary and thread relationship - @lowmegatron · 2025-11-29 original
The author promotes the Hypothyroid Masterclass, a video course with a support community covering practical testing, nutrition and dosing concepts. The post mainly lists the module titles. The embedded lowmegatron post contains only an emoji and a link.
Source summary and thread relationship - @lowmegatron · 2025-12-03 own thread gap
lowmegatron promotes his Hypothyroid Masterclass for people told their labs are normal who still feel hypothyroid. He lists on-demand modules on thyroid testing, conversion, supplementation, nutrition, stress and thyroid-affecting drugs, and mentions a support community.
Source summary and thread relationship - @lowmegatron · 2025-12-05 original
The author claims zinc is overlooked in thyroid status and may independently contribute to hypothyroid hair loss. He cites studies on zinc preventing exercise-related drops in thyroid hormones, zinc opposing melatonin's thyroid suppression, and zinc raising T3. He speculates zinc helps T4-to-T3 conversion.
Source summary and thread relationship - @lowmegatron · 2025-12-11 original
The author argues that oxidized LDL drives atherosclerosis and related cardiovascular events, and that linoleic acid from seed oils is oxidized by lipid peroxidation, which hypothyroidism increases. The post quotes Ray Peat on Broda Barnes' rabbit work and thyroid supplementation, plus excerpts from two papers on LDL oxidizability and thyroid function. The embedded quote, from lowmegatron, claims raised blood free fatty acids cause inflammation and impair artery dilation.
Source summary and thread relationship - @lowmegatron · 2025-12-14 original
Author states hypothyroidism increases adrenaline, quoting Ray Peat on adrenaline sustaining blood sugar and body temperature while disturbing sleep and speeding the heart. A quote from PMID 4766338 says thyroid hormone depresses noradrenaline and adrenaline secretion by blocking production at the cellular level. The embedded post from lowmegatron claims experimental hypothyroidism raised stress hormones and histamine, and that adding T3 to T4 improved anxiety, depression and quality of life.
Source summary and thread relationship - @lowmegatron · 2025-12-14 original
Quoted Ray Peat passage arguing that standard thyroid blood tests (T4, TSH) use ranges so wide that nearly everyone counts as normal. He says this traces to the protein-bound iodine test, later shown not to reflect thyroid function, and that the doctrine that only about 5% of people are hypothyroid persisted anyway.
Source summary and thread relationship - @lowmegatron · 2025-12-15 original
The author says high-dose zinc supplementation normalized T3 and lowered reverse T3 in people with zinc deficiency, and that zinc deficiency may cause hypothyroid symptoms by impairing T4-to-T3 conversion. The author notes this was a high dose in confirmed zinc deficiency. The embedded post (lowmegatron) lists a thyroid T3 checklist.
Source summary and thread relationship - @lowmegatron · 2025-12-15 original
The post quotes Ray Peat saying elevated TSH goes with elevated prolactin, that thyroid hormone supplementation usually corrects prolactin, and that calcium and vitamin D help balance prolactin, parathyroid hormone and cortisol. The post author adds that low thyroid hormone raises TRH, which stimulates TSH and prolactin. The embedded quoted post describes a case report of subclinical hypothyroidism with hyperprolactinemia and galactorrhea that resolved on levothyroxine.
Source summary and thread relationship - @lowmegatron · 2025-12-16 own thread
lowmegatron promotes his Hypothyroid Masterclass Group, listing video modules on hypothyroidism symptoms and causes, blood tests and their problems, pulse and temperature, T3 activity, autoimmunity, conversion, reverse T3, T4/NDT/T3 supplementation, nutrition (iron, iodine, selenium, PUFA), stress, and drugs affecting thyroid hormones.
Source summary and thread relationship - @lowmegatron · 2025-12-17 original
The author argues that a 1°C lower core temperature, reflecting low thyroid hormone activity, could add about 120 lb over a decade and that hypothyroidism induces a hibernation-like state. The post describes Broda Barnes's basal temperature test and BMR as thyroid indicators, with cited thresholds. The embedded Ray Peat quote criticizes TSH/T4 reference ranges and the history of the protein-bound iodine test.
Source summary and thread relationship - @lowmegatron · 2025-12-17 original
The author argues that some hypothyroidism is reversible with iodine restriction and that excess iodine is as harmful as deficiency. They cite a study in which 12 of 22 patients became euthyroid after 3 weeks of iodine restriction, and in which reintroducing 25 mg iodine daily made them hypothyroid again. They add Ray Peat and a review on excess iodine and autoimmune thyroiditis. They say selenium or vitamin E reduce the risk but do not fully prevent it. The embedded post from lowmegatron covers iodine intake and hypothyroidism rates in Japan and risk factors for iodine-induced thyroid dysfunction.
Source summary and thread relationship - @lowmegatron · 2025-12-29 own thread
lowmegatron argues that questions about hypothyroidism lack one-size-fits-all answers and that anyone offering broad solutions doesn't understand the problem. He promotes his Hypothyroid Masterclass Course, described as 31 short video modules, and lists the topics covered (tests, conversion, reverse T3, T4/NDT/T3 supplementation, nutrients, PUFA, stress, diet, drugs).
Source summary and thread relationship - @lowmegatron · 2026-01-03 original
The author describes selenium as required for thyroid hormone conversion and as protective of the thyroid. They say deficiency may cause hypothyroid-like symptoms and that supplementation may lower thyroid antibodies in autoimmune thyroid disease, help Graves' eye disease, and speed recovery of thyroid hormones in acute stress. They also list selenium-rich foods and note an upper limit of 400 mcg/day.
Source summary and thread relationship - @lowmegatron · 2026-01-03 original
The author asserts that low thyroid hormone decreases immunity and that thyroid hormone needs may increase in winter. The post supports this with quoted statements from Broda Barnes about thyroid therapy, fewer infections and thyroidectomized rabbits, and a Ray Peat statement that people on thyroid supplements often need four times as much in December as in July.
Source summary and thread relationship - @lowmegatron · 2026-01-03 original
The author argues that vitamin A deficiency disrupts thyroid function (higher TSH, goiter, reduced iodine uptake and hormone synthesis/conversion). Support is quoted review and trial excerpts and two PMIDs. The embedded quoted post from Metabolicmonstr gives an anecdote of a low vitamin A diet followed by worse eyesight and TSH rising from 1 to 21.
Source summary and thread relationship - @lowmegatron · 2026-01-12 original
Magnesium deficiency impairs thyroid function via decreased hormone conversion, thyroid enlargement, and reduced iodide uptake; low serum magnesium predicts Hashimoto's antibodies and hypothyroidism; Ray Peat explanation of magnesium's role in energy metabolism and thyroid hormone function.
Source summary and thread relationship - @lowmegatron · 2026-01-20 original
Normal TSH range explanation for unexplained infertility. Extended Ray Peat quotation on arbitrary TSH and T4 reference ranges, historical context of thyroid testing from protein-bound iodine test through current standards, and doctrine limiting population identified as needing thyroid.
Source summary and thread relationship - @lowmegatron · 2026-01-21 original
Critique of thyroid hormone cancer studies; distinguishes T4 (inactive) from T3 (active); argues T4-only supplementation suppresses T3 and increases cancer risk, while T3 in end-stage cancer prolongs survival.
Source summary and thread relationship - @lowmegatron · 2026-02-02 original
Ray Peat quote on historical research linking hypothyroidism to atherosclerosis via thyroid supplementation and cholesterol normalization, with embedded study on TSH and arterial stiffness in postmenopausal women.
Source summary and thread relationship - @lowmegatron · 2026-02-02 original
Kelp capsules suppress thyroid function via excessive iodine intake, with mechanism of iodine-induced hypothyroidism. Embedded post details iodine restriction reversibility of hypothyroidism in some patients, lipid peroxidation role, and Ray Peat commentary on excess iodine toxicity and autoimmune thyroiditis.
Source summary and thread relationship - @lowmegatron · 2026-02-04 own thread
lowmegatron advises getting sufficient iodine. He says deficiency can lower thyroid levels, high doses can cause hypothyroidism, hyperthyroidism or autoimmunity in susceptible people, the RDA is 150 mcg and intakes above 300 mcg daily may pose risks. He also says X-ray contrast media can trigger problems and that seafood and dairy are good sources.
Source summary and thread relationship - @lowmegatron · 2026-02-04 own thread
lowmegatron advises limiting goitrogens, which he says can interfere with thyroid hormone levels before a goiter is visible. He names cruciferous vegetables and soy as the main offenders, says cooking reduces them and says iodine insufficiency increases their effect.
Source summary and thread relationship - @lowmegatron · 2026-02-10 original
Author presents case of 86-year-old with elevated TSH after starting Iodoral (high-potency iodine supplement) prescribed by naturopath; TSH escalated to 99 after 1 month despite levothyroxine dose increase; TSH normalized after Iodoral cessation. Includes explanation of Wolff-Chaikoff effect and recovery mechanism with quoted study text.
Source summary and thread relationship - @lowmegatron · 2026-02-11 original
Quoted Ray Peat claims that diet and hormones interact; magnesium uptake requires adequate vitamin D and T3; T3 production requires selenium and sugar; pregnenolone and progesterone support T3 effects; cyproheptadine blocks stress mediators from hormonal-nutritional deficiencies; excess phosphate relative to calcium and magnesium creates tension.
Source summary and thread relationship - @lowmegatron · 2026-02-17 original
Single-word post 'Iodine' followed by embedded quote reporting personal adverse experience with high-dose iodine (5mg daily) causing hyperthyroidism with elevated T4.
Source summary and thread relationship - @lowmegatron · 2026-02-19 original
Author reports that over-the-counter thyroid supplements (glandular and herbal) contain variable and undisclosed amounts of thyroid hormones T3 and T4. Cites study finding nine of ten products contained detectable T3 (ranging 1.3–25 mcg), five contained T4 (0.5–22 mcg). Herbal products contained 100–240 mcg iodine and 150–1000 mg tyrosine per capsule, with specific examples showing recommended doses delivering substantial hormone amounts.
Source summary and thread relationship - @lowmegatron · 2026-02-26 original
Selenium supplementation (200 mcg sodium selenite) helps lower Hashimoto's antibodies; 25% of women achieved normal antibody levels compared to 4× placebo; improves inflammatory activity in autoimmune thyroiditis; recommends checking baseline selenium intake before supplementing due to risk of excess.
Source summary and thread relationship - @lowmegatron · 2026-03-04 original
Author provides historical narrative of iodine's identification (1812) and thyroid use (1816); embeds extensive quoted content on iodine's adverse effects, importance of caution, mechanisms of iodine-induced hypothyroidism, and the distinction between iodine deficiency and excess.
Source summary and thread relationship - @lowmegatron · 2026-03-09 original
Author lists micronutrients, macronutrients, and lifestyle factors (sleep, stress) claimed to optimize thyroid hormones and prevent T3 suppression. Quotes lowmegatron on cortisol's anti-thyroid mechanisms.
Source summary and thread relationship - @lowmegatron · 2026-03-12 original
Testosterone supplementation reduces thyroid antibodies (TPOAb and TgAb) in men with low testosterone and Hashimoto's disease. Selenium alone also reduces antibodies but testosterone produces greater reduction.
Source summary and thread relationship - @lowmegatron · 2026-03-14 original
Author lists interventions reported to lower thyroid antibodies (TPOAb, TGAb) with effect sizes, including near-infrared light, vitamin D, selenium, vitamin C, testosterone in deficient men, and levothyroxine; notes LDN, gluten removal, and dairy removal help a minority.
Source summary and thread relationship - @lowmegatron · 2026-03-16 original
Author traces historical discovery of thyroid hormone-induced weight loss from 1890s iodothyrin to modern T3 studies, noting iodothyrin as active thyroid gland extract containing T3; embeds lowmegatron post comparing T3 and levothyroxine on weight loss and LDL.
Source summary and thread relationship - @lowmegatron · 2026-03-19 original
Selenium deficiency causes thyroid hormone problems and insulin resistance. In type 2 diabetes patients with coronary heart disease, 200 mcg selenium for 8 weeks improved insulin sensitivity and reduced inflammation (decreased insulin, HOMA-IR, hs-CRP; increased QUICKI, TAC). In hypothyroid patients on thyroid hormone, HOMA-IR decreased and insulin sensitivity improved. Author recommends checking intake via Cronometer before supplementing, as excess selenium is harmful.
Source summary and thread relationship - @lowmegatron · 2026-03-19 original
Author cites a pilot study showing Brazil nut supplementation increased thyroid hormone in selenium-deficient hemodialysis patients; explains selenium's role in thyroid hormone conversion and autoimmune thyroid conditions; advises checking selenium intake before supplementing.
Source summary and thread relationship - @lowmegatron · 2026-03-24 original
Iodocasein is a thyroid-hormone-like modified milk protein formerly used in animal agriculture and contaminating some NDT/Armour thyroid supplements; derived from periodocasein made by heating milk and iodine; author cautions against unknown thyroid-hormone-like substances.
Source summary and thread relationship - @lowmegatron · 2026-03-26 original
Ray Peat's critique of thyroid testing history: protein-bound iodine test (1940s) was later proven invalid; TSH and T4 ranges remain inappropriately broad, maintaining doctrine that only 5% need thyroid despite abandoning the invalid test that established this threshold.
Source summary and thread relationship - @lowmegatron · 2026-03-31 original
Pre-1940 diets contained natural thyroid gland (≈30 mg daily equivalent) from cooking whole animals; modern diet lacks this thyroid source and contains pro-estrogen, antithyroid seed oils, contributing to hypothyroidism, high estrogen, and parasympathetic overactivity.
Source summary and thread relationship - @lowmegatron · 2026-04-09 original
High iodine intake in Japan is associated with increased hypothyroidism prevalence; iodine restriction reversed hypothyroidism in 55% of patients, and reintroduction of high-dose iodine reinstated hypothyroidism in some cases.
Source summary and thread relationship - @lowmegatron · 2026-04-12 original
Comprehensive explanation of selenium's role in thyroid hormone conversion and autoimmune thyroid disease. Covers mechanisms in acute stress, effects in Hashimoto's via RCT and case study, effects in Graves' disease and thyroid eye disease, synergy with myo-inositol, and recommended dosing.
Source summary and thread relationship - @lowmegatron · 2026-04-15 original
Ray Peat personal account of improved sleep quality and energy after starting thyroid supplementation, with spontaneous reduced coffee consumption.
Source summary and thread relationship - @lowmegatron · 2026-04-28 original
List of interventions reported to improve insulin sensitivity with supporting references; embedded quote on thyroid-insulin pathways in hypothyroidism.
Source summary and thread relationship - @lowmegatron · 2026-05-06 original
Author presents research on subclinical hypothyroidism, TSH involvement in insulin resistance via inflammation and TLR4 signaling, and a list of interventions that may improve insulin sensitivity including thyroid hormone correction, supplements, and lifestyle factors.
Source summary and thread relationship - @lowmegatron · 2026-05-06 original
Author attributes to Ray Peat a mechanism explaining poor body temperature response to thyroid medication: stress hormones shifting T4 metabolism to reverse T3, and emphasizes selenium sufficiency for T4-to-T3 conversion.
Source summary and thread relationship - @lowmegatron · 2026-05-08 original
Author shares Ray Peat quote about thyroid supplementation form (USP thyroid containing both T4 and T3) preventing stress-induced hypothyroidism and arrhythmias compared to Cytomel monotherapy.
Source summary and thread relationship - @lowmegatron · 2026-05-20 original
OTC thyroid supplements and desiccated thyroid products have highly variable thyroid hormone content; some contain no hormones while others contain up to 25 mcg T3 or 22 mcg T4 per dose; herbal products often contain undisclosed thyroid hormones.
Source summary and thread relationship - @lowmegatron · 2026-05-24 original
Case report of Japanese man developing hypothyroidism from daily povidone iodine gargling, with recovery after cessation and relapse after excessive kombu (kelp) consumption. Includes detailed clinical markers and discussion of iodine-induced hypothyroidism prevalence in Japan.
Source summary and thread relationship - @lowmegatron · 2026-05-26 original
Author lists sixteen factors that can impair thyroid hormone response: elevated free fatty acids, low total cholesterol, levothyroxine monotherapy, inappropriate T3 dosing, empty-stomach T3 administration, wrong T4:T3 ratio, TSH-only dosing, micronutrient insufficiencies (sodium, magnesium, calcium, retinol, zinc, selenium, vitamin D), high polyunsaturated fat intake, estrogen dominance, protein imbalance, and iron/iodine imbalance. Embedded post emphasizes carbohydrate's role in hepatic T3 production.
Source summary and thread relationship - @lowmegatron · 2026-06-06 original
Sharing a post about selenium's role in thyroid hormone conversion and autoimmune thyroid conditions; notes Brazil nut supplementation study in hemodialysis patients showing thyroid hormone improvement, with caution about excess selenium.
Source summary and thread relationship - @lowmegatron · 2026-06-09 original
Iodine balance is critical in hypothyroidism; excessive iodine can cause or worsen thyroid dysfunction. Studies show iodine restriction normalizes TSH and increases free T4 in subclinical hypothyroidism. High intake defined as >1000 μg/day or urine iodine exceeding reference range (8.6–41.3 μmol/g creatinine). Antioxidants (selenium, vitamin C, E) reduce oxidative stress from excess iodine but do not eliminate risk. Some individuals tolerate high-iodine protocols; others develop hypothyroidism or hyperthyroidism rapidly (Wolff-Chaikoff effect, Jod-Basedow phenomenon).
Source summary and thread relationship - @lowmegatron · 2026-06-12 original
lowmegatron says selenium deficiency can cause curly hair and nail changes that reverse when selenium is corrected. The post cites two men in case reports, in the context of elemental diets or total parenteral nutrition, and notes that copper deficiency and other factors can cause similar changes.
Source summary and thread relationship - @lowmegatron · 2026-06-16 own thread
lowmegatron says iodine is needed for thyroid hormone synthesis and deficiency can cause low thyroid levels. He says high doses can cause hypothyroidism, hyperthyroidism or autoimmunity in susceptible people, names low selenium and genetics as risk factors, cites a 150 mcg RDA and a risk above 300 mcg daily, and lists seafood and dairy as sources.
Source summary and thread relationship - @lowmegatron · 2026-06-16 own thread
lowmegatron says goitrogens can interfere with thyroid hormone levels before a goiter appears, names cruciferous vegetables and soy as main offenders, says cooking reduces them, and says iodine insufficiency worsens their effect.
Source summary and thread relationship - @lowmegatron · 2026-06-18 original
Repost of MelRoBuilds describing previous trial on desiccated Armour thyroid without effect and indicating intent to try a new experiment.
Source summary and thread relationship - @1immortals1 · 2026-06-27 original
Substantive explanation of iodine deficiency's return in developed world despite historical salt iodization; identifies specific causes (shift to non-iodized premium salts, bromine replacing iodine in bread, perchlorate contamination) and resulting subclinical hypothyroidism symptoms; claims iodine supports metabolism, cancer prevention, and brain development.
Source summary and thread relationship - @lowmegatron · 2026-06-28 original
Shared Ray Peat quote dismissing iodine skin test as unscientific due to reduction by vitamin C and other compounds; embedded post describes case of iodine-induced hypothyroidism from povidone iodine gargling and subsequent relapse from excess kombu/kelp intake, with detailed clinical markers showing recovery.
Source summary and thread relationship - @lowmegatron · 2026-06-29 original
User shares embedded anecdote from KamilBaszczyk1 about resolving hypothyroid symptoms by reducing iodine intake from supplements and salt after consulting a GPT chatbot about diet analysis.
Source summary and thread relationship - @lowmegatron · 2026-07-06 original
Near-infrared light therapy reduces thyroid volume in Hashimoto's disease; combined with vitamin D (if serum <40 ng/mL) and 100 mcg oral selenium; 4x more patients reached normal thyroid volume; includes embedded Ray Peat quote about diet context.
Source summary and thread relationship - @lowmegatron · 2026-07-07 original
Selenomethionine supplementation (200 mcg daily) during and after pregnancy reduces thyroid inflammation, TPO antibodies, and postpartum thyroid dysfunction in women with elevated TPO antibodies. Direct quotation from published study provided with specific outcome percentages and lab guidance on plasma selenium adequacy ranges.
Source summary and thread relationship - @lowmegatron · 2026-07-07 original
Observational studies show inverse association between dietary iodine intake and remission rates in Graves' hyperthyroidism. Higher iodine intake correlates with lower remission probability, higher antibody titers, and higher medication requirements. Research suggests low-iodine diet may reduce thyroid hormone production and lower medication doses needed for treatment.
Source summary and thread relationship - @lowmegatron · 2026-07-10 original
Author reports study findings on vitamin D supplementation reducing thyroid peroxidase antibodies in Hashimoto's patients. Embedded quoted post by lowmegatron discusses near-infrared light therapy combined with supplements reducing thyroid volume and improving function in Hashimoto's.
Source summary and thread relationship - @lowmegatron · 2026-07-10 original
Ray Peat quoted on thyroid hormone T3's role in eliminating edema and treating carpal tunnel syndrome through swelling reduction, versus conventional surgical approach. Embedded post by lowmegatron discusses hypothyroidism-induced waterlogging of median nerve tissue and reversibility with levothyroxine treatment.
Source summary and thread relationship - @lowmegatron · 2026-07-14 original
Low serum magnesium is associated with 3-4x increased likelihood of hypothyroidism, Hashimoto's disease, and thyroglobulin antibody positivity. Mechanisms involve immune dysregulation, cellular oxidative stress, energy metabolism, and mitochondrial function. Relationship may be bidirectional. Magnesium supplementation can improve thyroid function.
Source summary and thread relationship - @lowmegatron · 2026-07-15 original
Author clarifies that carbonation in magnesium bicarbonate water is only needed to form the compound; water can be consumed flat. Embedded post from lowmegatron describes magnesium bicarbonate water preparation method and rationale.
Source summary and thread relationship - @lowmegatron · 2026-07-15 original
Magnesium improves iodine uptake, thyroid hormone synthesis, and T4-to-T3 conversion; deficiency worsens hypothyroidism. Quoted study on magnesium supplementation effects in animal experiments and enzymatic mechanisms.
Source summary and thread relationship - @1immortals1 · 2026-07-15 original
Iodine insufficiency in 74% of population causes metabolic slowdown, fatigue, brain fog, and weight gain by preventing thyroid hormone production. Explains iodine structure in T3/T4, dietary sources and modern deficiency, brain and tissue effects, and recommends 150-500 mcg daily with selenium.
Source summary and thread relationship - @1immortals1 · 2026-07-18 original
Author claims raw beef liver is a complete multivitamin replacement, the most nutrient-dense food by any measure, containing exceptionally high levels of B12, vitamin A (preformed retinol), CoQ10, and bioavailable minerals; recommends 100g twice weekly with dosing options and pricing.
Source summary and thread relationship - @lowmegatron · 2026-07-23 original
T3 signaling reflects energy and nutritional abundance. Supplementing thyroid hormone in a malnourished body is cautioned against; small doses of T3 (50 mcg) without adequate nutrition compared to fasting in terms of inefficacy.
Source summary and thread relationship - @lowmegatron · 2026-07-24 original
Ray Peat on thyroid hormone T4-to-T3 conversion: requires glucose, selenium, adequate protein, and specific nutrient ratios; discusses mineral balance, estrogen interference, and optimal dosing strategies for thyroid replacement therapy including desiccated thyroid and synthetic combinations.
Source summary and thread relationship - @lowmegatron · 2026-07-26 own thread
Reference list for the author's claim that fluoride lowers thyroid hormones and that taurine, calcium and tamarind are protective. It lists rat, human observational, rabbit and cattle studies on fluoride, thyroid dysfunction and fluoride excretion. The quoted context is a separate post on prenatal fluoride exposure and lower IQ (PMID 28937959).
Source summary and thread relationship - @lowmegatron · 2026-07-29 original
Three-month randomized controlled trial in 70 women with Hashimoto's antibodies: selenium supplementation (200 mcg sodium selenite daily) achieved 25% remission of antibodies vs. 6% placebo; TPO antibodies decreased 34% vs. 12% placebo; thyroid structure normalized in responders.
Source summary and thread relationship - @lowmegatron · 2026-07-29 original
Ray Peat reports that chewing 5 mcg Cytomel (synthetic T3) rapidly restores memory within 3–5 minutes, with peak effect at 90 minutes. Dose of 25 mcg daily caused hypothyroid arrhythmia (heart pauses every 6 seconds lasting 1–2 seconds) within weeks; 10 mcg Cytomel immediately restored normal rhythm. Thyroid supplements had similar effect in Peat's acquaintances with arrhythmia and circulation problems from hypothyroidism.
Source summary and thread relationship - @lowmegatron · 2026-07-29 original
Ray Peat reports consuming 50 cups of coffee daily for years while hypothyroid to manage stress, migraines, and fatigue. Within days of starting thyroid supplement, coffee craving disappeared and intake spontaneously dropped to 4–5 cups daily. Peat reframes this not as addiction but as homeostatic adaptation to hypothyroidism that resolved with thyroid correction.
Source summary and thread relationship - @lowmegatron · 2026-07-30 original
Higher serum selenium in older adults associated with higher T3, lower TSH, and lower T4, indicating improved thyroid hormone conversion and function. Study concludes reduced T4-to-T3 peripheral conversion related to impaired selenium status in elderly. Thyroid hormone conversion enzymes require selenium.
Source summary and thread relationship - @lowmegatron · 2026-07-30 original
Author lists interventions shown to lower thyroid antibodies in autoimmune thyroiditis, citing multiple peer-reviewed studies. Cautions that selenium and vitamin D optimization requires measurement, not blind supplementation.
Source summary and thread relationship - @lowmegatron · 2026-08-07 original
Bulleted list of dietary and lifestyle interventions for optimizing thyroid hormone conversion, including carbohydrate intake, stress management, micronutrient adequacy, avoiding mold/fluoride, and T3/T4 hormone balance considerations.
Source summary and thread relationship - @lowmegatron · 2026-08-08 original
Ray Peat quoted explaining that stress (cortisol and adrenaline) can shift T4 metabolism toward reverse T3 formation; emphasizes selenium as crucial nutrient for T4 to T3 conversion across all tissues requiring seafood intake (~weekly).
Source summary and thread relationship - @lowmegatron · 2026-08-10 original
Selenium concentration is highest in the thyroid and deficiency is associated with hypothyroidism, subclinical hypothyroidism, Hashimoto's, Graves' disease, and thyroid cancer. Embedded quote attributes to lowmegatron that selenium is required for thyroid hormone conversion and calms autoimmune thyroid processes.
Source summary and thread relationship - @lowmegatron · 2026-08-11 original
Quotation from McGavack's clinical text states methimazole is the least toxic and most efficient antithyroid compound compared to iodine, propylthiouracil, and methylthiouracil. Embedded quote from lowmegatron describes iodine-induced hypothyroidism from habitual Povidone-iodine gargling and excessive kelp/kombu consumption, with case study of Japanese man whose TSH normalized when iodine sources were removed.
Source summary and thread relationship - @1immortals1 · 2026-08-12 original
Salt restriction causes more harm than benefit. Table salt is chemically processed and mineral-depleted; mineral-rich salts (sea salt, Redmond Real Salt, Himalayan) contain trace minerals essential for adrenal function, muscle contraction, neuron firing, stomach acid production, and hydration. The sodium-health relationship follows a J-curve; low intake is as dangerous as high intake.
Source summary and thread relationship - @lowmegatron · 2026-08-12 original
Selenium is essential for tissue-level thyroid hormone T3 production. Consuming shellfish, seafood, halibut, cod, or sole provides sufficient selenium to maintain active tissue thyroid hormone supply.
Source summary and thread relationship - @1immortals1 · 2026-09-03 original
Iodine is essential for thyroid hormone production; iodine insufficiency (not deficiency) affects ~2 billion people globally and contributes to metabolic slowdown, cognitive impairment, cold intolerance, and hormone-sensitive tissue health. Modern low-salt dietary trends reduced iodine intake after salt iodization eliminated goiters in the 1920s.
Source summary and thread relationship - @1immortals1 · 2026-09-08 original
Iodine deficiency caused by shift from iodized table salt to sea salt and Himalayan salt; iodine essential for thyroid T3/T4 production and metabolic function; historical public health success of iodization in 1924 reversed by recent salt trends; recommendations for iodized salt or kelp supplementation.
Source summary and thread relationship - @jamesbondwisdom · 2026-09-12 original
jamesbondwisdom claims thyroid dysfunction, both hypo- and hyperthyroidism, causes diffuse hair loss that is reversible once corrected, and that dermatologists rarely check it. It says T3 controls anagen duration. It argues that TSH alone misses subclinical dysfunction, recommends a full panel (TSH, free T3, free T4, TPO and TG antibodies), and asserts an optimal TSH of 1.0-2.0.
Source summary and thread relationship - @lowmegatron · 2026-09-15 original
Historical account of Chinese thyroid treatment in 652 AD using seaweed and thyroid gland-containing animal parts ('yeh'). Notes iodine deficiency as historical context. Embedded quote discusses Natural Desiccated Thyroid (NDT) formulations, T4/T3 ratios, mechanism, and brand comparisons.
Source summary and thread relationship - @lowmegatron · 2026-09-15 original
General health optimization guidance recommending 'basic' nutrient coverage before exotic interventions. Lists common deficient micronutrients: magnesium, potassium, selenium, vitamins D, C, E, K1/2, thiamine. Advises testing and dietary sources before supplementation. Cites foundational lifestyle: sunlight, sleep, walking. Embedded quote discusses interventions that lower thyroid antibodies.
Source summary and thread relationship - @lowmegatron · 2026-09-16 original
Ray Peat recommended oysters for hormonal health due to zinc and selenium content. Zinc replenishment normalizes T3 thyroid hormone and lowers reverse T3 in zinc-deficient individuals. Selenium supports thyroid hormone conversion and reduces thyroid antibodies. Some people find thyroid hormones work better when incorporating oysters. Study citation provided on zinc role in thyroid metabolism.
Source summary and thread relationship - @lowmegatron · 2026-09-17 original
Multiple overlooked factors contribute to insulin resistance beyond diet and exercise, including carrageenan, thyroid hormones, minerals, stress, endotoxin, light exposure, vitamins, sleep, and movement.
Source summary and thread relationship - @lowmegatron · 2026-09-18 own thread
lowmegatron quotes a rat study (PMID 4133501) reporting a close positive correlation between serum magnesium and thyroid activity as measured by radioiodide handling. Magnesium deficiency or loading did not change thyroid cyclic AMP or hormone release in vitro. Radioiodide accumulation was stimulated by magnesium loading and inhibited by deficiency. The post is a continuation of a thread arguing that magnesium depletion harms thyroid function.
Source summary and thread relationship - @lowmegatron · 2026-09-21 original
Progesterone increases expression of genes the thyroid uses for iodine uptake, hormone synthesis and growth. This effect is progesterone-receptor-dependent. Evidence shows free T4 increases and TSH tends lower during progesterone treatment in women.
Source summary and thread relationship - @1immortals1 · 2026-09-25 original
Piperine from black pepper increases bioavailability of most supplements by 30-2000% by inhibiting hepatic cytochrome P450 enzymes (CYP3A4); dramatically increases curcumin absorption from 1% to 20%; effect lasts 1-2 hours post-ingestion.
Source summary and thread relationship